10.1016/s1474-4422(21)00252-0 Lancet Neurol
In the coming years, it will be revealing for researchers to build on lab-based evidence in well-designed, large-scale clinical trials
Vitamin B12 Benefits Outside of its role in supporting weight loss, Vitamin B12 has a variety of health benefits: Brain Health Support: Vitamin B12 is essential for maintaining healthy nerve cells, which play a role in helping neurotransmitters produce and communicate Immune System Boost: Adequate levels of vitamin B12 help support a stronger, healthier immune system Promotes Heart Health: B12 helps regulate the bodys levels of homocysteine, amino acids that can increase your risk of heart disease Bone Health Support: Vitamin B12 also plays a role in maintaining your bone health, which can help prevent the onset of conditions like osteoporosis Vitamin B12 injections offer immediate improvements, helping increase your energy levels and improve your mood so that you can stay focused on and committed to your weight loss goals
Concurrently, liver insulin resistance promotes de novo lipogenesis ( de novo lipogenesis through sterol regulatory element-binding protein 1c (SREBP-1c) activation, increasing the synthesis of triglycerides and very-low-density lipoproteins (VLDL), contributing to MASLD and systemic dyslipidemia Figure 4 (50, 52, 53)
